Abstract Triple-negative breast cancer (TNBC) is a clinically challenging and molecularly heterogenous breast cancer subgroup.Here, we investigate the DNA methylation landscape of TNBC.By analyzing tumor methylome profiles and accounting for the genomic context of CpG methylation, we divide TNBC into two epigenetic subtypes corresponding to a Basal
We present data on amphibian density, species richness, and diversity from a 7140-ha area consisting of 200 ponds in the Midwestern U.S.that represents most of the possible lentic aquatic breeding habitats common in this region.Our study includes all possible breeding sites with natural and anthropogenic disturbance processes that can be missing fr
The response of a ship or other vessel to surface sea waves, including extreme waves, may compromise crew and vessel safety and long-term operational capability.Herein, a novel high-fidelity numerical time-dependent simulation approach is presented using Smoothed Spot Treatment Particle Hydrodynamics (SPH) for modelling sea waves coupled with Finit
Body image concerns revolving around body ideals (thin ideal, muscular ideal) are widespread among women.Whereas a Spot Treatment stronger preoccupation with ideal physical appearance is often assumed for narcissistic women, previous empirical findings have been mixed.Following a tripartite structure of agentic, antagonistic, and neurotic narcissis